Hepatic toxicity: Hyperbilirubinemia, hepatic cholestasis, increases in liver enzymes, fatal hepatic failure, jaundice. Taking this medicine after the expiration date can make you seriously ill. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. If it is almost time for your next dose, minocin mundliche skip the missed dose and take the medicine at the next regularly scheduled time. However, certain organisms eg, some staphylococci, and Acinetobacter species may be more susceptible to minocycline and doxycycline than to tetracycline. As with standardized dilution techniques, diffusion methods require the use of laboratory control microorganisms that are used to control the technical aspects of the laboratory procedures.