Of patients had systolic pressure fall of 30 mmHg or more from supine to standing, or standing systolic pressure below 90 mmHg with fall of at least 20 mmHg, compared to of placebo group. If high blood pressure is not treated, over hytrin overdosis time, the increased pressure can damage blood vessels or it can cause the heart to work too hard and may decrease the flow of blood to the heart, brain, and kidneys. If you are pregnant or plan to become pregnant, notify your doctor immediately. If you notice other effects not listed above, contact your doctor or pharmacist. Doses over 20 mg do not appear to provide further blood pressure effect and doses over 40 mg have not been studied. During controlled clinical trials, patients receiving terazosin monotherapy had small but statistically significant decrease fall compared to placebo in total cholesterol and the combined low-density and very-low-density lipoprotein fractions. The long-term effects of HYTRIN on the incidence of surgery, acute urinary obstruction or other complications of BPH are yet to be determined.