Peak serum concentrations above basal values were reached within to hours following oral administration of single doses of. Should, however, persistent calcitriol aus indien and markedly elevated serum calcium levels occur, there are variety of therapeutic alternatives which may be considered, depending on the patient underlying condition. PTH may encourage calcitriol activation but calcitriol instructs the parathyroid glands to cut PTH secretion. It is practically insoluble in water, soluble in alcohol and in fatty oils. Discontinuation of supplemental calcium and low-calcium diet are also indicated in accidental overdosage. PRECAUTIONS: Tell your doctor if you have: heart disease, kidney disease or kidney stones, coronary artery disease hardening of the arteries.